Anti-IDH1 Antibody (34074)

$308.00

Host Quantity Applications Species Reactivity Data Sheet  
Mouse 100ul IHC Human
SKU: 34074 Categories: , ,
Overview
Product Name Anti-IDH1 Antibody (34074)
Description Anti-IDH1 Mouse Monoclonal Antibody
Target IDH1
Species Reactivity Human
Applications IHC
Host Mouse
Clonality Monoclonal
Clone ID G132.1
Isotype IgG1
Immunogen Synthetic peptide corresponding to the region of human IDH1 that includes a point mutation at residue 132 where Arginine (R) is changed to Histidine (H)
Properties
Form Liquid
Concentration Lot Specific
Formulation Tris buffer, pH 7.3-7.7, 1% BSA, 0.1% sodium azide.
Buffer Formulation Tris
Buffer pH pH 7.3-7.7
Buffer Anti-Microbial 0.1% Sodium Azide
Buffer Protein Stabilizer 1% Bovine Serum Albumin
Format Purified
Purification Purified by immunoaffinity chromatography
Specificity Information
Specificity Human R132H-IDH1. Reactivity with other species has not been investigated.
Target Name Isocitrate dehydrogenase [NADP] cytoplasmic
Target ID IDH1
Uniprot ID O75874
Alternative Names Cytosolic NADP-isocitrate dehydrogenase, IDP, NADP(+)-specific ICDH, Oxalosuccinate decarboxylase
Gene Name IDH1
Sequence Location Cytoplasm, cytosol, Peroxisome
Research Areas Cancer research
Application Images
Description Immunohistochemistry: use at a dilution of 1:100-1:200 on formalin-fixed, paraffin-embedded samples after heat-induced epitope retrieval at pH 9 for 10-30 minutes. Detection of IDH1 R132H in human astrocytoma with #34074 diluted 1:100-1:200.
Additional Information
Handling
Storage Store at 2-8°C. Do not freeze.
Dilution Instructions Dilute in PBS or medium that is identical to that used in the assay system.
Application Instructions

Immunohistochemistry: use at a dilution of 1:100-1:200 on formalin-fixed, paraffin-embedded samples after heat-induced epitope retrieval at pH 9 for 10-30 minutes.
References & Data Sheet