Mikrogen Diagnostik recomWell HEV IgM ELISA Kit (5005)
$632.00
SKU: 5005
Categories: Infectious Disease Test Kits and Positive Controls, MIKROGEN Products
Overview
Product Name Mikrogen Diagnostik recomWell HEV IgM ELISA Kit (5005)
Description Enzyme immunoassay with antigens produced by recombinant techniques for the detection of IgG and IgM antibodies against hepatitis E Virus (HEV) in human serum or plasma.
Product is intended for research use.
Product is intended for research use.
Target Human HEV IgM
Species Reactivity Hepatitis E virus
Assay Type Indirect ELISA
Applications ELISA
Associated Products recomWell HEV IgG ELISA Kit (5004)
Properties
Background Hepatitis E virus (HEV) is one of the leading causes of faecal-orally acquired hepatitis worldwide, usually resulting from contaminated drinking water. In developed countries, hepatitis E is usually transmitted through infected pork, which was not sufficiently cooked. HEV can be transmitted through blood products, blood transfusions and organ donation. In Europe most cases of hepatitis E are caused by the HEV genotype 3.The HEV infection usually remains symptomatic. Acute hepatitis E is an illness with a clinical presentation comparable to hepatitis A. Typical signs of hepatitis E include flu-like symptoms, vomiting, diarrhoea, fever, arthralgia and headache usually associated with a rise in liver enzyme values. Cholestatic jaundice that develops during the course of disease can persist for several weeks. HEV infection is usually self-limiting. In endemic regions in a high percentage of cases HEV infections during pregnancy follow a fulminant course, accompanied by a high mortality rate of approx. 20%. In males and non-pregnant females the mortality rate is 0.5% - 4.0%.For the recomWell HEV IgG, IgM purified recombinant antigens of the HEV genotypes 1 and 3 are used, thus guaranteeing reproducibly high sensitivity and specificity. The other HEV-genotypes 2 and 4 can be diagnosed by crossreactivity. The recomWell HEV IgG, IgM is highly suitable as a screening assay, especially in case of negative resulting hepatitis A-C-screening assay findings.
Sample Type Serum, plasma, whole blood
Assay Resolution See Figure
Components
10X Wash Buffer | 100 mL |
Dilution Buffer | 125 mL |
TMB Substrate | 12 mL |
Stop Slution | 12 mL |
Instuctions for Use | 1 Each |
Evaluation Form | 1 Each |
Microplate Sealing Tape | 2 Each |
Microtiter Plate | 12 x 8 Wells |
Positive Control | 450 uL |
Cut-Off Control | 450 uL |
Negative Control | 450 uL |
Anti-Human IgM Conjugate | 500 uL |
Specificity Information
Target ID Human HEV IgM
Research Areas Infectious Disease
Additional Information
Additional Information Additional Mirkogen Kit Information
Handling
Storage Store at 2-8°C.
References & Data Sheet
Data Sheet Download PDF Data Sheet