Anti-DENTT Antibody (56316)

$376.00

Host	Quantity	Applications	Species Reactivity	Data Sheet
Rabbit	100ug	WB	Human

SKU: 56316 Categories: Antibody Products, Neuroscience and Signal Transduction Antibodies, Products

Overview

Product Name Anti-DENTT Antibody (56316)

Description Anti-DENTT Rabbit Polyclonal Antibody

Target DENTT

Species Reactivity Human

Applications WB

Host Rabbit

Clonality Polyclonal

Immunogen Human DENTT protein.

Properties

Form Liquid

Concentration Lot Specific

Formulation PBS, pH 7.4.

Buffer Formulation Phosphate Buffered Saline

Buffer pH pH 7.4

Format Purified

Purification Purified by immunoaffinity chromatography

Specificity This antibody recognizes human DENTT (Differentially Expressed Nucleolar TGF-b1 Target) protein, a gene product expressed in several normal tissues with the highest level of expression in brain. DENTT is involved in responses mediated by TGF-b1 and has distinct domains for direction to different subnuclear locations.

Target Name Testis-specific Y-encoded-like protein 2

Target ID DENTT

Uniprot ID Q9H2G4

Alternative Names TSPY-like protein 2, Cell division autoantigen 1, Cutaneous T-cell lymphoma-associated antigen se20-4, CTCL-associated antigen se20-4, Differentially-expressed nucleolar TGF-β1 target protein, Nuclear protein of 79 kDa, NP79

Gene Name TSPYL2

Sequence Location Nucleus, Cytoplasm

Biological Function Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression. {PubMed:11395479, PubMed:17317670}.

Research Areas Neuroscience

Handling

Storage This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.

Dilution Instructions Dilute in PBS or medium which is identical to that used in the assay system.

Application Instructions Immunoblotting: use at 1:500-1:1,000 dilution. In immunoblots, a band of approximately 77 kD is detected.

Data Sheet