Anti-MUC12 Antibody (56233)

$376.00

Host	Quantity	Applications	Species Reactivity	Data Sheet
Rabbit	100ug	WB	Human

SKU: 56233 Categories: Antibody Products, Cancer Research Antibodies, Products

Overview

Product Name Anti-MUC12 Antibody (56233)

Description Anti-MUC12 Rabbit Polyclonal Antibody

Target MUC12

Species Reactivity Human

Applications WB

Host Rabbit

Clonality Polyclonal

Immunogen Peptide corresponding to aa 541-555 of human Mucin 12.

Properties

Form Liquid

Concentration Lot Specific

Formulation PBS, pH 7.4.

Buffer Formulation Phosphate Buffered Saline

Buffer pH pH 7.4

Format Purified

Purification Purified by peptide immuno-affinity chromatography

Specificity This antibody recognizes human MUC12 (Mucin 12), a novel mucin that appears to be involved in epithelial cell growth regulation. MUC12 is down-regulated in colorectal cancers.

Target Name Mucin-12

Target ID MUC12

Uniprot ID Q9UKN1

Alternative Names MUC-12, Mucin-11, MUC-11

Gene Name MUC12

Sequence Location Membrane, Single-pass type I membrane protein

Biological Function Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF-beta in intestinal epithelium. {PubMed:17058067}.

Research Areas Cancer research

Handling

Storage This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.

Dilution Instructions Dilute in PBS or medium which is identical to that used in the assay system.

Application Instructions Immunoblotting: use at 1:500-1:1,000 dilution.

Data Sheet