Anti-MUC12 Antibody (56232)

$376.00

Host	Quantity	Applications	Species Reactivity	Data Sheet
Rabbit	100ug	WB	Human

SKU: 56232 Categories: Antibody Products, Cancer Research Antibodies, Products

Overview

Product Name Anti-MUC12 Antibody (56232)

Description Anti-MUC12 Rabbit Polyclonal Antibody

Target MUC12

Species Reactivity Human

Applications WB

Host Rabbit

Clonality Polyclonal

Immunogen Peptide corresponding to aa 10-24 of human Mucin 12.

Properties

Form Liquid

Concentration Lot Specific

Formulation PBS, pH 7.4.

Buffer Formulation Phosphate Buffered Saline

Buffer pH pH 7.4

Format Purified

Purification Purified by peptide immuno-affinity chromatography

Specificity This antibody recognizes human MUC12 (Mucin 12), a novel mucin that appears to be involved in epithelial cell growth regulation. MUC12 is down-regulated in colorectal cancers.

Target Name Mucin-12

Target ID MUC12

Uniprot ID Q9UKN1

Alternative Names MUC-12, Mucin-11, MUC-11

Gene Name MUC12

Sequence Location Membrane, Single-pass type I membrane protein

Biological Function Involved in epithelial cell protection, adhesion modulation, and signaling. May be involved in epithelial cell growth regulation. Stimulated by both cytokine TNF-alpha and TGF-beta in intestinal epithelium. {PubMed:17058067}.

Research Areas Cancer research

Handling

Storage This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.

Dilution Instructions Dilute in PBS or medium which is identical to that used in the assay system.

Application Instructions Immunoblotting: use at 1:500-1:1,000 dilution.

Data Sheet