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Anti-Corticotropin Releasing Factor Antibody (56101)

$469.00

Host Quantity Applications Species Reactivity Data Sheet  
Mouse 100ug ELISA Human, Rat
SKU: 56101 Categories: , ,
Overview
Product Name Anti-Corticotropin Releasing Factor Antibody (56101)
Description Anti-Corticotropin Releasing Factor Mouse Monoclonal Antibody
Target Corticotropin Releasing Factor
Species Reactivity Human, Rat
Applications ELISA
Host Mouse
Clonality Monoclonal
Clone ID 4H9
Isotype IgG1
Immunogen Purified human/rat corticotropin-releasing factor (CRF, Sigma).
Properties
Form Liquid
Concentration Lot Specific
Formulation PBS, pH 7.4.
Buffer Formulation Phosphate Buffered Saline
Buffer pH pH 7.4
Format Purified
Purification Purified by immunoaffinity chromatography
Specificity Information
Specificity These antibodies react specifically with CRF. There is no cross-reactivity with bovine serum albumin, insulin, ovalbumin, or epidermal growth factor. These two antibodies recognize different epitopes on CRF. Dissociation constants = 10-9 M for 56101and 1.5 x 10-8 M for 56102.
Target Name Corticoliberin
Target ID Corticotropin Releasing Factor
Uniprot ID P06850
Alternative Names Corticotropin-releasing factor, CRF, Corticotropin-releasing hormone
Gene Name CRH
Sequence Location Secreted
Biological Function Hormone regulating the release of corticotropin from pituitary gland (By similarity). Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity). {UniProtKB:P06296, UniProtKB:Q8CIT0}.
Research Areas Neuroscience
Application Images
Additional Information
Handling
Storage These antibodies are stable for at least one (1) year at -20°C to -70°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
Dilution Instructions Dilute in PBS or medium which is identical to that used in the assay system.
Application Instructions These antibodies may be used in immunoassays to detect and quantitate CRF. Other applications are under investigation.
References & Data Sheet
References Kravchenko and Furalev. 1994. Hybridoma 13: 59-64
Furalev et al. 1994. Biochem Biophys Res Com 204: 823-834.