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Mikrogen Diagnostik recomWell HEV IgM ELISA Kit (5005)

$632.00

Host Quantity Applications Species Reactivity Data Sheet  
96 Tests ELISA Hepatitis E virus
SKU: 5005 Categories: ,
Overview
Product Name Mikrogen Diagnostik recomWell HEV IgM ELISA Kit (5005)
Description Enzyme immunoassay with antigens produced by recombinant techniques for the detection of IgG and IgM antibodies against hepatitis E Virus (HEV) in human serum or plasma.

Product is intended for research use.
Target Human HEV IgM
Species Reactivity Hepatitis E virus
Assay Type Indirect ELISA
Applications ELISA
Properties
Background Hepatitis E virus (HEV) is one of the leading causes of faecal-orally acquired hepatitis worldwide, usually resulting from contaminated drinking water. In developed countries, hepatitis E is usually transmitted through infected pork, which was not sufficiently cooked. HEV can be transmitted through blood products, blood transfusions and organ donation. In Europe most cases of hepatitis E are caused by the HEV genotype 3.The HEV infection usually remains symptomatic. Acute hepatitis E is an illness with a clinical presentation comparable to hepatitis A. Typical signs of hepatitis E include flu-like symptoms, vomiting, diarrhoea, fever, arthralgia and headache usually associated with a rise in liver enzyme values. Cholestatic jaundice that develops during the course of disease can persist for several weeks. HEV infection is usually self-limiting. In endemic regions in a high percentage of cases HEV infections during pregnancy follow a fulminant course, accompanied by a high mortality rate of approx. 20%. In males and non-pregnant females the mortality rate is 0.5% - 4.0%.For the recomWell HEV IgG, IgM purified recombinant antigens of the HEV genotypes 1 and 3 are used, thus guaranteeing reproducibly high sensitivity and specificity. The other HEV-genotypes 2 and 4 can be diagnosed by crossreactivity. The recomWell HEV IgG, IgM is highly suitable as a screening assay, especially in case of negative resulting hepatitis A-C-screening assay findings.
Sample Type Serum, plasma, whole blood
Assay Resolution See Figure
Components
10X Wash Buffer100 mL
Dilution Buffer125 mL
TMB Substrate12 mL
Stop Slution12 mL
Instuctions for Use1 Each
Evaluation Form1 Each
Microplate Sealing Tape2 Each
Microtiter Plate12 x 8 Wells
Positive Control450 uL
Cut-Off Control450 uL
Negative Control450 uL
Anti-Human IgM Conjugate500 uL
Specificity Information
Target ID Human HEV IgM
Research Areas Infectious Disease
Application Images
Additional Information
Handling
Storage Store at 2-8°C.
References & Data Sheet