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Anti-Cyclin E1 Antibody (3123)

$376.00

Host Quantity Applications Species Reactivity Data Sheet  
Rabbit 100ug ELISA Human
SKU: 3123 Categories: , ,
Overview
Product Name Anti-Cyclin E1 Antibody (3123)
Description Anti-Cyclin E1 Rabbit Polyclonal Antibody
Target Cyclin E1
Species Reactivity Human
Applications ELISA
Host Rabbit
Clonality Polyclonal
Immunogen Peptide corresponding to amino acids 43-52 of cyclin E1.
Properties
Form Liquid
Concentration Lot Specific
Formulation PBS, pH 7.4
Buffer Formulation Phosphate Buffered Saline
Buffer pH pH 7.4
Format Purified
Purification Purified by immunoaffinity chromatography
Specificity Information
Specificity This antibody recognizes human cyclin E1, a protein (approx. 50 kD) expressed in elevated levels in human tumor cells. Cyclin E1 controls the initiation of DNA synthesis by activating cdk2, and i expression of cyclin E1 is upregulated by the E7 oncoprotein.
Target Name G1/S-specific cyclin-E1
Target ID Cyclin E1
Uniprot ID P24864
Gene Name CCNE1
Gene ID 898
Accession Number NP_001229
Sequence Location Nucleus
Biological Function Essential for the control of the cell cycle at the G1/S (start) transition. {PubMed:7739542}.
Research Areas Cancer Research
Application Images
Additional Information
Handling
Storage This antibody is stable for at least one (1) year at -70°C. Avoid multiple freeze- thaw cycles.
Dilution Instructions Dilute in PBS or medium which is identical to that used in the assay system.
Application Instructions Immunoblotting: use at 1:500-1:1,000.
References & Data Sheet