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Anti-FBG2 Antibody (28119)

$397.00

Host Quantity Applications Species Reactivity Data Sheet  
Rabbit 100ug WB Human, Mouse, Rat
SKU: 28119 Categories: , ,
Overview
Product Name Anti-FBG2 Antibody (28119)
Description Anti-FBG2 (F Box 2) Rabbit Polyclonal Antibody
Target FBG2
Species Reactivity Human, Mouse, Rat
Applications WB
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to amino acids 268-284 of human FBG2.
Properties
Form Liquid
Concentration Lot Specific
Formulation PBS, pH 7.4.
Buffer Formulation Phosphate Buffered Saline
Buffer pH pH 7.4
Format Purified
Purification Purified by Protein G affinity chromatography
Specificity Information
Specificity This antibody recognizes human, mouse, and rat FBG2.
Target Name F-box only protein 6
Target ID FBG2
Uniprot ID Q9NRD1
Alternative Names F-box protein that recognizes sugar chains 2, F-box/G-domain protein 2
Gene Name FBXO6
Sequence Location Cytoplasm
Biological Function Substrate-rPubMed:18203720, PubMed:19716789}.
Research Areas Neuroscience
Background F-box proteins, critical components of the conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F- box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.
Application Images
Additional Information
Handling
Storage This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.
Dilution Instructions Dilute in PBS or medium that is identical to that used in the assay system.
Application Instructions Immunoblotting : use at 1-5ug/ml dilution. A band of approximately 34 kDa is detected.

These are recommended concentrations. User should determine optimal concentration for their applications.
References & Data Sheet