Anti-Resistin Antibody (26105)
$376.00
SKU: 26105
Categories: Antibody Products, Hormones and Serum Protein Antibodies, Products
Overview
Product Name Anti-Resistin Antibody (26105)
Description Anti-Resistin Rabbit Polyclonal Antibody
Target Resistin
Species Reactivity Human
Applications WB
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to aa 79-90 of human resistin.
Properties
Form Liquid
Concentration Lot Specific
Formulation PBS, pH 7.4.
Buffer Formulation Phosphate Buffered Saline
Buffer pH pH 7.4
Format Purified
Purification Purified by immunoaffinity chromatography
Specificity Information
Specificity This antibody specifically recognizes human resistin, a product of white adipose tissue believed to induce insulin resistance in obesity and regulate adipocyte differentiation. This hormone appears to be the link between obesity and type 2 diabetes.
Target Name Resistin
Target ID Resistin
Uniprot ID Q9HD89
Alternative Names Adipose tissue-specific secretory factor, ADSF, C/EBP-ε-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-α-like 2, Cysteine-rich secreted protein FIZZ3
Gene Name RETN
Sequence Location Secreted
Biological Function Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells (By similarity). Potentially links obesity to diabetes (By similarity). Promotes chemotaxis in myeloid cells (PubMed:15064728). {UniProtKB:Q99P87, PubMed:15064728}.
Research Areas Hormones/Proteins
Handling
Storage This antibody is stable for at least one (1) year at -20°C to -70°C. Store antibody in appropriate aliquots to avoid multiple freeze-thaw cycles.
Dilution Instructions Dilute in PBS or medium that is identical to that used in the assay system.
Application Instructions Immunoblotting: use at 1:500-1:1,000 dilution. In immunoblots, a band of approximately 14 kD is detected.
References & Data Sheet
Data Sheet Download PDF Data Sheet