Anti-Factor V Light Chain Antibody (19701)

$538.00

Host	Quantity	Applications	Species Reactivity	Data Sheet
Mouse	250ug	ELISA,IHC,Autorad	Human

SKU: 19701 Categories: Antibody Products, Coagulation Factor Antibodies, Factor V Antibodies, Products

Overview

Product Name Anti-Factor V Light Chain Antibody (19701)

Description Anti-Factor V Light Chain Mouse Monoclonal Antibody

Target Factor V Light Chain

Species Reactivity Human

Applications ELISA,IHC,Autorad

Host Mouse

Clonality Monoclonal

Clone ID B38

Isotype IgG1

Immunogen Purified human Factor V.

Properties

Form Liquid

Concentration Lot Specific

Formulation PBS, pH 7.4

Buffer Formulation Phosphate Buffered Saline

Buffer pH pH 7.4

Format Purified

Purification Purified by Protein G affinity chromatography

Specificity This antibody recognizes the F1F2 polypeptide of human Factor Va light chain.

Target Name Coagulation factor V

Target ID Factor V Light Chain

Uniprot ID P12259

Alternative Names Activated protein C cofactor, Proaccelerin, labile factor [Cleaved into: Coagulation factor V heavy chain; Coagulation factor V light chain]

Gene Name F5

Sequence Location Secreted

Biological Function Central regulator of hemostasis. It serves as a critical cofactor for the prothrombinase activity of factor Xa that results in the activation of prothrombin to thrombin.

Research Areas Coagulation factors.

Background Coagulation cofactor V (Factor V) is a high molecular weight glycoprotein that performs several critical functions in regulating hemostasis. In its thrombin-activated form (FVa) it interacts with Factor Xa and Ca+2 to form the prothrombinase complex. This complex catalyzes the formation of thrombin from prothrombin at rates substantially higher than Factor Xa alone.

Handling

Storage This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.

Dilution Instructions Dilute in PBS or medium that is identical to that used in the assay system.

Application Instructions Western blotting: a band of approx. 74kDa is detected.

References Gewirtz AM et al. 1986 Blood 67: 1639-1648. Annamalai AE et al. 1987 Blood 70: 139-156.

PMID 2423159
2439148

Data Sheet