Anti-XAB2 Antibody (56247)

$376.00

Host	Quantity	Applications	Species Reactivity	Data Sheet
Rabbit	100ug	WB	Human

SKU: 56247 Categories: Antibody Products, Cancer Research Antibodies, Products

Overview

Product Name Anti-XAB2 Antibody (56247)

Description Anti-XAB2 Rabbit Polyclonal Antibody

Target XAB2

Species Reactivity Human

Applications WB

Host Rabbit

Clonality Polyclonal

Immunogen Peptide corresponding to aa 840-855 of human XAB2 protein.

Properties

Form Liquid

Concentration Lot Specific

Formulation PBS, pH 7.4.

Buffer Formulation Phosphate Buffered Saline

Buffer pH pH 7.4

Format Purified

Purification Purified by immunoaffinity chromatography

Specificity This antibody recognizes human XAB2 protein (XPA-binding protein 2) which appears to be involved in transcription- coupled DNA repair and transcription. XAB2 binds to XPA, a key factor in nucleotide excision repair pathways.

Target Name Pre-mRNA-splicing factor SYF1

Target ID XAB2

Uniprot ID Q9HCS7

Alternative Names Protein HCNP, XPA-binding protein 2

Gene Name XAB2

Sequence Location Nucleus

Biological Function Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28502770, PubMed:28076346). Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing (PubMed:10944529, PubMed:17981804). {PubMed:10944529, PubMed:11991638, PubMed:17981804, PubMed:28076346, PubMed:28502770}.

Research Areas Cancer research

Handling

Storage This antibody is stable for at least one (1) year at -70°C. Avoid multiple freeze- thaw cycles.

Dilution Instructions Dilute in PBS or medium which is identical to that used in the assay system.

Application Instructions Immunoblotting: use at 1:500-1:1,000 dilution. A band of approximately 100 kD (the monomeric form) is detected.

Data Sheet