Specificity Any Human. In immunoblots a band of 85kDa is detected and may represent precursor. Lower mw bands are detected in some cell lines, including Jurkat, and may represent the processed mature protein. This antibody recognizes all human, mouse, and rat FLIP splice variants. This antibody recognizes all three isoforms of human, mouse and rat PHAP, including PHAP I (32kDa), PHAP I2a, and PHAP III (35kDa). This antibody recognizes an epitope at the C-terminus of human Bmf (Bcl-2-Modifying Factor), a novel BH3-only protein. In healthy cells, Bmf associates with the dynein light chain 2 component of the This antibody recognizes an epitope at the N-terminus of human Bmf (Bcl-2-Modifying Factor), a novel BH3-only protein. In healthy cells, Bmf associates with the dynein light chain 2 component of the This antibody recognizes full-length ARC (25 kD). This antibody recognizes full-length Bim (23kDa) of human, mouse, and rat. This antibody recognizes full-length DcR2 (34kDa). This antibody recognizes full-length human and mouse DR3 (59kDa). This antibody recognizes full-length human and mouse DR5 (57kDa). This antibody recognizes full-length human caspase-10 (59kDa). Since the sequences at C- termini of FLICE2 and Mch4 are different, this antibody recognizes only the FLICE2 form of caspase-10. This antibody recognizes full-length human caspase-9 (46kDa). This antibody recognizes full-length human DR3 (59kDa). This antibody recognizes full-length human DR4 (57kDa). This antibody recognizes full-length human RAIDD (22kDa). This antibody recognizes full-length human, monkey, and mouse Daxx (120kDa). This antibody recognizes full-length human, mouse, and rat FLIPalpha (55kDa). This antibody recognizes full-length human, mouse, and rat RICK (60kDa). This antibody recognizes full-length human, mouse, and rat ZIP kinase (52kDa). This antibody recognizes full-length mouse and human Apaf1 (115-130kDa). This antibody recognizes full-length mouse CAD (40kDa). This antibody recognizes human AIF (67 kDa). This antibody recognizes human ALIX protein. This antibody recognizes human and bovine Annexin 1. This antibody recognizes human and mouse Acinus (220 kD). This antibody recognizes human and mouse Bcl-3. This antibody recognizes human and mouse BNIP3. This antibody recognizes human and mouse Caspase-4 (36kDa). This antibody recognizes human and mouse FLASH (220kDa). This antibody recognizes human and mouse MADD (200-220 kD). This antibody recognizes human and mouse PHAP I (32kDa). The sequence of rat PHAP I is identical to human PHAP I. This antibody recognizes human and mouse PUMA (23kDa). This antibody recognizes human and mouse PUMA (23kDa). A lower molecular weight band at 16kDa is detected in MOLT4 and U937 cell lysates and probably represents the PUMA-β protein. This antibody recognizes human ARTS (Apoptosis Related Protein in image Signaling Pathway), a novel mito-chondrial septin-like protein. ARTS translocates to the cell nucleus when apoptosis occurs. It This antibody recognizes human ASC (25kDa). This antibody recognizes human ASK1 (155kDa). This antibody recognizes human Bcl10 (31kDa). This antibody recognizes human CARD9, a novel CARD (Caspase Recruitment Domain)- containing protein that interacts with the CARD activation domain of Bcl-10. CARD9 associates with Bcl-10 to form a co This antibody recognizes human CIDE-3. Sequence homology to the mouse CIDE-3 homolog, FSP27, is 93%. This antibody recognizes human CIDE-A (23kDA) and does not cross-react with CIDE-B. This antibody recognizes human DFF40 (40kDa). This antibody recognizes human DR4 (57kDa). This antibody recognizes human DR6 (68kDa). This antibody recognizes human DRAK1 (50kDa). No cross-reactivity with DRAK2, DAP or ZIP kinases. This antibody recognizes human DRAK2 (45kDa). No cross-reactivity with DRAK1, DAP or ZIP kinases. This antibody recognizes human FLIPγ (35kDa) and FLIPδ(25kDa) but not FLIPα or FLIPβ. This antibody recognizes human GRIM-19 (Genes associated with Retinoid-IFN- induced Mortality), a nuclear protein that functions as a cell death regulatory molecule. Antisense expression of GRIM-19 c This antibody recognizes human IP6K2. This antibody recognizes human Livin (33kDa). This antibody recognizes human MAP-1 (Modulator of Apoptosis Protein), a novel Bax-associating protein. MAP-1 mediates caspase-dependent apoptosis in mammalian cells when overexpressed. MAP-1 homodim This antibody recognizes human RAIDD (22kDa). This antibody recognizes human Survivin (17kDa). This antibody recognizes human TRAIL. This antibody recognizes human TRICK2. This antibody recognizes human, mouse and rat PHAP I (32kDa) and PHAP III (35kDa). This antibody recognizes human, mouse and rat PHAP I (32kDa), and does not cross-react with PHAP I2a or PHAP III. This antibody recognizes human, mouse and rat PHAP III (35kDa). This antibody recognizes human, mouse, and rat AIF (67 kD). This antibody recognizes human, mouse, and rat AIF (67 kDa). This antibody recognizes human, mouse, and rat Apaf1 (130kDa). This antibody recognizes human, mouse, and rat ARC (25 kD). This antibody recognizes human, mouse, and rat BAFF (approx. 38kDa). This antibody recognizes human, mouse, and rat caspase-12 (approx. 53kDa). This antibody recognizes human, mouse, and rat caspase-13 (43kDa). This antibody recognizes human, mouse, and rat Caspase-8 (18kDa). This antibody recognizes human, mouse, and rat DAPK2 (approx. 42kDa) and does not cross- react with DAPK. This antibody recognizes human, mouse, and rat DC-UbP. This antibody recognizes human, mouse, and rat DcR1 (65kDa). This antibody recognizes human, mouse, and rat DcR3 (33kDa). This antibody recognizes human, mouse, and rat DEDAF (32kDa). This antibody recognizes human, mouse, and rat DFF40/CAD (40kDa). This antibody recognizes human, mouse, and rat EndoG (Endonuclease G) an enzyme that is activated by apoptotic stimuli and is able to induce nucleosomal fragmentation of DNA independently of caspase This antibody recognizes human, mouse, and rat F1A (70kDa). This antibody recognizes human, mouse, and rat ILP-2 (33kDa). This antibody recognizes human, mouse, and rat RICK (60kDa). This antibody recognizes human, mouse, and rat Smac (25kDa). This antibody recognizes human, mouse, and rat SODD (60kDa). This antibody recognizes human, mouse, and rat TACE, and 80-130kDa bands are detected in immunoblots. These bands may represent mature protein, precursor, and glycosylated TACE. This antibody recognizes human, mouse, rat, and bovine ubiquitin. Other species have not been investigated. This antibody recognizes monomeric human and mouse Bnip3L. A band of 40kDa is detected in immunoblots. This antibody recognizes mouse and rat RIP3 (57kDa). This antibody recognizes mouse CIDE-A (25kDa) and does not cross-react with CIDE-B. This antibody recognizes mouse CIDE-B (25kDa) and does not cross-react with CIDE-A. This antibody recognizes mouse FLIPL form (55kDa) but not FLIPS form. This antibody recognizes mouse Survivin (17kDa). This antibody recognizes non-cleaved (45kDa) and cleaved DFF. This antibody recognizes non-cleaved (45kDa) and cleaved DFF45. This antibody recognizes non-cleaved (45kDa) and cleaved mouse ICAD. This antibody recognizes the proenzyme of human DNase II (40kDa).
