Anti-SERPINB10 Antibody (56312)

$362.00

Host	Quantity	Applications	Species Reactivity	Data Sheet
Rabbit	100ug	WB	Human

SKU: 56312 Categories: Antibody Products, Neuroscience and Signal Transduction Antibodies, Products

Overview

Product Name Anti-SERPINB10 Antibody (56312)

Description Anti-SERPINB10 Rabbit Polyclonal Antibody

Target SERPINB10

Species Reactivity Human

Applications WB

Host Rabbit

Clonality Polyclonal

Immunogen Peptide corresponding to aa 316-330 of human SERPINB10 protein.

Properties

Form Liquid

Concentration Lot Specific

Formulation PBS, pH 7.4.

Buffer Formulation Phosphate Buffered Saline

Buffer pH pH 7.4

Format Purified

Purification Purified by immunoaffinity chromatography

Specificity This antibody recognizes human SERPINB10 protein, a gene product that is expressed in human bone marrow cells. Members of the human serpin family regulate a diverse array of serine and cysteine proteinases associated with fibrinolysis, coagulation, inflammation, cell mobility, cellular differentiation, and apoptosis. Most serpins are secreted and found in blood and extracellular fluids. A subset of the serpin family, the ov-serpins, are intracellular as well.

Target Name Serpin B10

Target ID SERPINB10

Uniprot ID P48595

Alternative Names Bomapin, Peptidase inhibitor 10, PI-10

Gene Name SERPINB10

Sequence Location Nucleus. Cytoplasm. Note=Mostly found in the nucleus.

Biological Function Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus. {PubMed:10871600, PubMed:7592909}.

Research Areas Neuroscience

Handling

Storage This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.

Dilution Instructions Dilute in PBS or medium which is identical to that used in the assay system.

Application Instructions Immunoblotting: use at 1:500-1:1,000 dilution. In immunoblots, a band of approximately 45 kD is detected.

Data Sheet