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Chromogranin A (26103P-5)

$169.00

Host Quantity Applications Species Reactivity Data Sheet  
5ug WB Human
SKU: 26103P-5 Categories: ,
Overview
Product Name Chromogranin A (26103P-5)
Description Recombinant Human CHGA produced in E. coli is a single non-glycosylated polypeptide chain containing 114 amino acidsaa 19-131) with a molecular weight of 12.8kDa.
Target Chromogranin A
Species Reactivity Human
Applications WB
Source Escherichia coli
Properties
Form Liquid
Concentration Lot Specific
Formulation Sterile-filtered solution in 20mM Tris-HCl, pH 8.0, and 10% glycerol.
Buffer Formulation 20 mM Tris
Buffer pH pH 8.0
Buffer Cryopreservative 10% glycerol
Purity Greater than 95% as determined by SDS- PAGE
Background Chromogranin A (CHGA) is a member of the neuroendocrine secretory protein family located in secretory vesicles of neurons and endocrine cells. CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides function as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides including chromostatin, betagranin, WE-14 and GE-25 are also derived from full-length CHGA. CHGA has numerous biological activities including antifungal and antimicrobial action, modulation of cell adhesion, and inhibition of parathyroid hormone secretion.
Specificity Information
Target Name Chromogranin-A
Target ID Chromogranin A
Alternative Names CHGA
Sequence MLPVNSPMNK GDTEVMKCIV EVISDTLSKP SPMPVSQECF ETLRGDERIL SILRHQNLLK ELQDLALQGA KERAHQQKKH SGFEDELSEV LENQSSQAEL KEAVEEPSSK DVME.
Background Chromogranin A (CHGA) is a member of the neuroendocrine secretory protein family located in secretory vesicles of neurons and endocrine cells. CHGA is a precursor to three biologically active peptides: vasostatin, pancreastatin, and parastatin. These peptides function as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides including chromostatin, betagranin, WE-14 and GE-25 are also derived from full-length CHGA. CHGA has numerous biological activities including antifungal and antimicrobial action, modulation of cell adhesion, and inhibition of parathyroid hormone secretion.
Application Images
Additional Information
Handling
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store at or below -20°C for longer periods of time. Addition of a carrier protein (such as 0.1% HSA or BSA) is recommended for long-term storage.
Dilution Instructions Dilute in PBS or medium that is identical to that used in the assay system.
References & Data Sheet