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Alpha Crystallin B (11073P-1000)

$1,514.00

Host Quantity Applications Species Reactivity Data Sheet  
1000ug WB Human
SKU: 11073P-1000 Categories: ,
Overview
Product Name Alpha Crystallin B (11073P-1000)
Description Recombinant Human CRYAB produced in E. coli is a single, non-glycosylated polypeptide chain containing 175 amino acids with a molecular weight of 20.2kDa.
Target Alpha Crystallin B
Species Reactivity Human
Applications WB
Source Escherichia coli
Properties
Form Liquid
Concentration Lot Specific
Formulation Sterile-filtered colorless solution contains 20mM Tris-HCl, pH 7.5, 50mM NaCl and 1mM EDTA.
Buffer Formulation 20 mM Tris
Buffer pH pH 7.5
Purity Greater than 95% as determined by SDS-PAGE and RP- HPLC
Background Alpha crystallins are composed of two gene products: alpha-A (acidic) and alpha-B (basic). Alpha crystallins are induced by heat shock and are members of the small heat shock protein family. They act as molecular chaperones. In addition, alpha crystallins have autokinase activity and play a role in intracellular architecture. Alpha crystalline B is expressed in many tissues and is associated with many neurological diseases.
Specificity Information
Target Name Alpha Crystallin B
Target ID Alpha Crystallin B
Alternative Names CRYAB
Sequence MDIAIHHPWI RRPFFPFHSP SRLFDQFFGE HLLESDLFPT STSLSPFYLR PPSFLRAPSWFDTGLSEMRL EKDRFSVNLD VKHFSPEELK VKVLGDVIEV HGKHEERQDE HGFISREFHRKYRIPADVDP LTITSSLSSD GVLTVNGPRK QVSGPERTIP ITREEKPAVT AAPKK
Background Alpha crystallins are composed of two gene products: alpha-A (acidic) and alpha-B (basic). Alpha crystallins are induced by heat shock and are members of the small heat shock protein family. They act as molecular chaperones. In addition, alpha crystallins have autokinase activity and play a role in intracellular architecture. Alpha crystalline B is expressed in many tissues and is associated with many neurological diseases.
Application Images
Additional Information
Handling
Storage Store at 4°C if entire vial will be used within 2-4 weeks. Store at or below -20°C for longer periods of time. For long term storage, addition of a carrier protein (0.1% HSA or BSA) is recommended.
Dilution Instructions Dilute in PBS or medium that is identical to that used in the assay system.
References & Data Sheet