Anti-Heme Oxygenase-2 Antibody (13063)

$466.00

Host Quantity Applications Species Reactivity Data Sheet  
Rabbit 100ug WB,IHC,IP Human, Mouse, Rat
SKU: 13063 Categories: , ,
Overview
Product Name Anti-Heme Oxygenase-2 Antibody (13063)
Description Anti-Heme oxygenase-2 (HO-2) Rabbit Polyclonal Antibody
Target Heme Oxygenase-2
Species Reactivity Human, Mouse, Rat
Applications WB,IHC,IP
Host Rabbit
Clonality Polyclonal
Immunogen Full-length native rat HO-2 purified from testes.
Properties
Form Liquid
Concentration Lot Specific
Formulation PBS, pH 7.4, 50% glycerol, 0.09% sodium azide.
Buffer Formulation Phosphate Buffered Saline
Buffer pH 7.4
Buffer Anti-Microbial 0.09% Sodium Azide
Buffer Cryopreservative 50% Glycerol
Format Purified
Purification Purified by protein A affinity chromatography
Specificity Information
Target Name Heme oxygenase 2
Target ID Heme Oxygenase-2
Uniprot ID P23711
Alternative Names HO-2, EC 1.14.14.18
Gene Name Hmox2
Accession Number NP_077363.1
Sequence Location Microsome. Endoplasmic reticulum.
Biological Function Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter.
Research Areas Enzymes
Application Images
Description Immunohistochemistry analysis using Rabbit Anti-HO-2 Polyclonal Antibody (13063). Tissue: Spinal cord. Species: Rat. Primary Antibody: Rabbit Anti-HO-2 Polyclonal Antibody (13063) at 1:1000.
Description Western blot analysis of Rat Brain cell lysates showing detection of HO-2 protein using Rabbit Anti-HO-2 Polyclonal Antibody (13063). Lane 1: Rat Brain lysate. Lane 2: Purified HO-2. Load: 10 µg. Primary Antibody: Rabbit Anti-HO-2 Polyclonal Antibody (13063) at 1:1000.
Additional Information
Handling
Storage Store at 2 - 8°C. Do not Freeze.
Dilution Instructions Dilute in PBS or medium that is identical to that used in the assay system.
Application Instructions Immunoblotting: use at 1ug/mL.Immunohistochemistsry: use at 1ug/mL.

These are recommended concentrations.

Endusers should determine optimal concentrations for their applications.
References & Data Sheet