Anti-DPP10 Antibody (28114)

$384.00

Host Quantity Applications Species Reactivity Data Sheet  
Rabbit 100ug WB,ELISA Human
SKU: 28114 Categories: , ,
Overview
Product Name Anti-DPP10 Antibody (28114)
Description Anti-DPP10 Rabbit Polyclonal Antibody
Target DPP10
Species Reactivity Human
Applications WB,ELISA
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to aa 521-539 of human DPP10.
Properties
Form Liquid
Concentration Lot Specific
Formulation PBS, pH 7.4.
Buffer Formulation Phosphate Buffered Saline
Buffer pH pH 7.4
Format Purified
Purification Purified by immunoaffinity chromatography
Specificity Information
Specificity This antibody recognizes human DPP10.
Target Name Inactive dipeptidyl peptidase 10
Target ID DPP10
Uniprot ID Q8N608
Alternative Names Dipeptidyl peptidase IV-related protein 3, DPRP-3, Dipeptidyl peptidase X, DPP X, Dipeptidyl peptidase-like protein 2, DPL2
Gene Name DPP10
Sequence Location Cell membrane, Single-pass type II membrane protein
Biological Function Promotes cell surface expression of the potassium channel KCND2 (PubMed:15454437). Modulates the activity and gating characteristics of the potassium channel KCND2 (PubMed:15454437). Has no dipeptidyl aminopeptidase activity (PubMed:12662155). {PubMed:12662155, PubMed:15454437, PubMed:15671030}.
Research Areas Neuroscience
Background The DPP10 gene encodes a homolog of dipeptidyl peptidases that cleave terminal dipeptides from cytokines and chemokines, and it presents a potential target for asthma therapy. The DPP10 protein shares features with members of the S9B family of DPP serine proteases which includes DPP4, an enzyme that participates in chemokine processing.
Application Images
Description QED Bioscience_Anti-DPP10 Antibody (28114)_1
Additional Information
Handling
Storage This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.
Dilution Instructions Dilute in PBS or medium that is identical to that used in the assay system.
Application Instructions Immunoblotting: use at 1-5ug/mL. A band of approx. 75 kDa is detected, however protein oligermization may occur.

These are recommended concentrations. User should determine optimal concentrations for their applications.
References & Data Sheet