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Anti-Asymmetric Dimethyl Arginine Antibody (90005)

$520.00

Host Quantity Applications Species Reactivity Data Sheet  
Mouse 100ug WB,IHC Asymmetric Dimethyl Arginine
SKU: 90005 Categories: , ,
Overview
Product Name Anti-Asymmetric Dimethyl Arginine Antibody (90005)
Description Anti-Asymmetric Dimethyl Arginine Mouse Monoclonal Antibody
Target Asymmetric Dimethyl Arginine
Species Reactivity Asymmetric Dimethyl Arginine
Applications WB,IHC
Host Mouse
Clonality Monoclonal
Clone ID 21C7
Isotype IgM
Immunogen Dimethyl-L-arginine
Properties
Form Lyophilized
Formulation Lyophilized, 0.1M Tris, 0.1M glycine, 2% sucrose, 1mg/ml.
Buffer Formulation Tris Buffer
Format Purified
Purification Purified by Protein A affinity chromatography
Specificity Information
Specificity This antibody reacts with free and bound ADMA. It does not cross-react with free or bound arginine or NG- monomethyl arginine.
Target ID Asymmetric Dimethyl Arginine
Research Areas Hormones/Proteins
Background Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by- product of continual protein modification processes in the cytoplasm of all human cells. It is closely related to L-arginine. ADMA interferes with L-arginine in the production of nitric oxide, a key chemical involved in normal endothelial function and, by extension, cardio- vascular health. Since raised levels of ADMA appear to be associated with adverse human health consequences for cardiovascular disease, metabolic diseases, and also a wide range of diseases of the elderly, the possible lowering of ADMA levels may have important therapeutic effects.
Application Images
Additional Information
Handling
Storage This product is stable for at least one (1) year at -20°C to -70°C. Reconstituted product should be stored in appropriate aliquots to avoid repeated freeze-thaw cycles.
Dilution Instructions Reconstitute lyophilized antibody using ultrapure to a final concentration no less than 100 ug/mL. Reconstitution with PBS or Tris buffer is acceptable if required. Protein carrier, biocide or cryopreservative can be added as needed. Aliquot and store at -20C for longterm storage. Dilute immediately prior to use.
Application Instructions Immunoblotting: use at 1-2ug/ml

Immunohistochemistry: use at 1-10ug/ml.

These are recommended concentrations.

End user should determine optimal concentrations for their applications.
References & Data Sheet