Anti-KLK4 Antibody (56237)

$376.00

Host	Quantity	Applications	Species Reactivity	Data Sheet
Rabbit	100ug	WB	Human

SKU: 56237 Categories: Antibody Products, Cancer Research Antibodies, Products

Overview

Product Name Anti-KLK4 Antibody (56237)

Description Anti-KLK4 Rabbit Polyclonal Antibody

Target KLK4

Species Reactivity Human

Applications WB

Host Rabbit

Clonality Polyclonal

Immunogen Peptide corresponding to aa 242-254 of human KLK4 protein.

Properties

Form Liquid

Concentration Lot Specific

Formulation PBS, pH 7.4.

Buffer Formulation Phosphate Buffered Saline

Buffer pH pH 7.4

Format Purified

Purification Purified by immunoaffinity chromatography

Specificity This antibody recognizes the gene product hk4 of human KLK4 (also known as KLK-L1), one of the many kallikrein serine proteases associated with carcinogenesis. KLK4 is up- regulated by androgens and progestins and has been associated with prostate and breast cancers and possibly with other cancers.

Target Name Kallikrein-4

Target ID KLK4

Uniprot ID Q9Y5K2

Alternative Names EC 3.4.21.-, Enamel matrix serine proteinase 1, Kallikrein-like protein 1, KLK-L1, Prostase, Serine protease 17

Gene Name KLK4

Sequence Location Secreted.

Biological Function Has a major role in enamel formation (PubMed:15235027). Required during the maturation stage of tooth development for clearance of enamel proteins and normal structural patterning of the crystalline matrix (By similarity). {UniProtKB:Q9Z0M1, PubMed:15235027}.

Research Areas Cancer research

Handling

Storage This antibody is stable for at least one (1) year at -70°C. Avoid multiple freeze- thaw cycles.

Dilution Instructions Dilute in PBS or medium which is identical to that used in the assay system.

Application Instructions Immunoblotting: use at 1:500-1:1,000 dilution. A band of approximately 39 kD is detected.

Data Sheet