Anti-HIV-1 gp120 Antibody (56012-500)
$467.00
SKU: 56012-500
Categories: Antibody Products, Infectious Disease Antibodies, Products
Overview
Product Name Anti-HIV-1 gp120 Antibody (56012-500)
Description Anti-HIV-1 gp120 (PNDmn) Mouse Monoclonal Antibody
Target HIV-1 gp120
Species Reactivity Hiv-1
Applications ELISA
Host Mouse
Clonality Monoclonal
Clone ID ANT-151
Isotype IgG1
Immunogen Recombinant gp120 (MN strain), a CCR5 and X4 tropic strain.
Properties
Form Lyophilized
Formulation PBS, pH 7.4, Lyophilized
Buffer Formulation Phosphate Buffered Saline
Buffer pH pH 7.4
Format Purified
Purification Ion exchange-purified
Specificity Information
Target ID HIV-1 gp120
Research Areas Infectious Disease
Background Human immunodeficiency virus (HIV) is a retrovirus that infects CD4+ T cells, macrophages and dendritic cells leaving infected individuals susceptible to various opportunistic infections. HIV is a member of the genus Lentivirus, part of the family of Retroviridae. Lentiviruses are transmitted as single-stranded, positive- sense, enveloped RNA viruses. Upon entry into a target cell, viral RNA is converted to double-stranded DNA by a virally encoded reverse transcriptase. Viral DNA is integrated into host cellular DNA by a virally encoded integrase. The virus may become latent or may continue to infect other susceptible cells.
Handling
Storage This antibody is stable for at least one year. Store lyophilized product at 4°C. After reconstitution, aliquot and store at -20°C. Avoid multiple freeze-thaw cycles.
Dilution Instructions Reconstitute with sterile H2O. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Application Instructions ELISA: use at 1-5ug/ml for binding to recombinant gp120.In vitro virus neutralization:
End user should determine optimal concentrations.
End user should determine optimal concentrations.
References & Data Sheet
Data Sheet Download PDF Data Sheet